What are the signs a company will be successful? WHAT they do and what they sell may be more important than HOW they do it.
Why? A 'WHAT' Innovation is a fundamental change to a product or service. It's never been done before so therefore it's hard to replicate and repeat. A 'HOW' innovation is just a change to the business model or how the business is done. While still novel and important, this is an edge the business will eventually loose as more competitors come to the scene.
Look for 'WHAT' not 'HOW'.
More from David George, a top Andreessen Horowitz Investor on the latest episode: https://www.youtube.com/watch?v=eA9XDRz51Zg